4-Unit Commercial Building for Sale on Main St in Salem, MO

Income-Producing Commercial Rental Property in Salem, Missouri

Located at 800 S. Main Street in Salem, Missouri, this commercial building offers 5,512 ± square feet of finished space across four rental units in a highly visible, high-traffic spot just off a state-maintained highway. Current tenants include a beauty salon, a financial advisor’s office, a real estate office and a radio station on the lower level, giving buyers a diverse mix of established businesses and built-in rental income. Owned and carefully maintained by the same family since 1965, the all-brick building combines a classic exterior with updated interiors and professional office space throughout.

Downtown Salem, MO Investment Property with New Roof

In the heart of downtown Salem, this Dent County investment property benefits from strong Main Street visibility, an asphalt driveway and plenty of parking for tenants, customers and staff. A new EPDM roof installed in 2026 adds value and peace of mind for the next owner. Whether you’re growing an investment portfolio or looking for a versatile, income-producing commercial building in a prime Salem, Missouri location, this property offers strong potential for investors and business owners alike.